¿ËÈÕ£¬¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðίÐû²¼ÁË2022Äê¶È»ù½ðÆÀÉóЧ¹û£¬Óɹú¼ÒÖصãÑз¢ÍýÏë“ÌúƤʯõú´ó¿µ½¡²úÆ·Ñз¢”Ê×ϯ¿Æѧ¼Ò£¬Õã½¹¤Òµ´óѧ¶þ¼¶Ñо¿Ô±¡¢²©µ¼³ÂËغìÖ÷³ÖÉ걨µÄÏîÄ¿——¡¶»ùÓÚ“Âѳ²-¸Î/³¦Öá”FSH/E2-SREBPsͨ·µÄÌúƤʯõú¹ú²ÝÒû¸ÄÉÆΧ¾ø¾ÆÚÖ¬´úлÔÓÂÒµÄ×÷ÓûúÖÆÑо¿¡·£¬»ñ¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðÃæÉÏÏîÄ¿Á¢ÏîÖ§³Ö¡£
¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðÊÇÎÒ¹úÖ§³Ö»ù´¡Ñо¿µÄÖ÷ÇþµÀ£¬Êǹú¼ÒÁ¢ÒìϵͳµÄÖ÷Òª×é³É²¿·Ö¡£´Ë´ÎÄÜÀֳɻñµÃ¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðÁ¢Ï¼È¿ªÍØÁËÌúƤʯõú»ù´¡Ñо¿ÁìÓòµÄÐÂʱÊÆ£¬Ò²ÎªÌúƤʯõúµÄÒ©ÎïÑо¿ºÍ¿ª·¢ÌṩÁËÀíÂÛÒÀ¾Ý¡£
¹ú²ÝÒû¸ÄÉÆÄÚÉø͸-ÃâÒß-´úлÔÓÂÒ
¾Ý³ÂËغìÏÈÈÝ£¬Ëæ×ÅÏÖ´úÉúÑÄˮƽµÄÌá¸ß£¬“¹ýʳ·Ê¸Êºñ攣¨¸ßÌÇ¡¢¸ßÖ¬¡¢¸ßµ¨¹Ì´¼µÈ£©¼ÓÖØΧ¾ø¾ÆÚ´úлÐÔÐÄѪ¹Ü¼²²¡±¬·¢Éú³¤£¬·ÀÖÎÐèÇó´ó¡£“ÉöÒõ¿÷Ðé¡¢¸ÎʧÊèй¡¢Æ¢Ê§½¡ÔË”ÊÇΧ¾ø¾ÆÚÖ¬´úлÔÓÂÒµÄÖ÷Òª²¡»ú£»ÏÖ´úҽѧÑо¿Åú×¢£¬ÄÚÉø͸-ÃâÒßϵͳÔÓÂÒ¡¢Âѳ²Ïà¹ØFSH/E2¼¤ËØˮƽʧºâ¡¢½éµ¼¸Î³¦Ö¬´úлÐźÅͨ·Òì³£¿ÉÄÜÊÇÆäÖ÷Òª·¢²¡»úÖÆ¡£
³ÂËغìÌåÏÖ£¬Ç°ÆÚÍŶÓÔÚ¹ú¼ÒÖصãÑз¢ÍýÏë“ÌúƤʯõú´ó¿µ½¡²úÆ·Ñз¢”ÏîÄ¿¼°¹ú¼Ò×ÔÈ»¿Æѧ»ù½ðµÈÏîÄ¿Ö§³ÖÏ£¬Á¢ÒìÐÔʵ¼ùºÍ¸»ºñÁË“Æ¢ð÷ÐÂÂÛ”“¹ýʳ·Ê¸Êºñζ”Ö´úлÐÔÐÄѪ¹Ü¼²²¡µÄ±æÖ¤ÂÛÖΣ¬Ñз¢µÄÌúƤʯõú¹ú²ÝÒûÈëÑ¡¹ú¼ÒÊ®ÈýÎå¿Æ¼¼Á¢Òì³É¼¨Õ¹¡£Ç°ÆÚÑо¿Åú×¢£¬¹ú²ÝÒû¿ÉÏÔןÄÉÆΧ¾ø¾ÆÚ“¹ýʳ·Ê¸Êºñζ”Ö¬´úлÔÓÂÒÄ£×Ó´óÊóµÄѪ֬ˮƽºÍ¸Î³¦²¡±ä£¬µ÷ÀíÄÚÉø͸ÃâÒßÒÔ¼°FSH/E2ˮƽ£¬µ«Æä×÷ÓûúÖÆÊÇ·ñÓë“Âѳ²-¸Î/³¦Öá”Ö¬´úлÏà¹ØÐźÅͨ·Ïà¹ØÄØ£¿
¸ÃÏîÄ¿¾ÍÊÇÔÚ´Ë»ù´¡ÉÏ£¬Ìá³ö¿Æѧ¼Ù˵£ºÌúƤʯõú¹ú²ÝÒû¾ßÓГ×ÌÒõÒæÉö¡¢½¡Æ¢Êè¸Î”µÄ¹¦Ð§£¬¿É¸ÄÉÆΧ¾ø¾ÆÚ“¹ýʳ·Ê¸Êºñζ”ËùÖµÄÖ¬´úлÔÓÂÒ£»Æä×÷ÓûúÖÆ¿ÉÄÜÊÇͨ¹ýµ÷ÀíÄÚÉø͸-ÃâÒßϵͳ£¬“Âѳ²-¸Î/³¦Öá”ÐźÅͨ·£¬´Ó¶ø¸ÄÉÆΧ¾ø¾ÆÚÖ¬´úл¡£ÎªÑéÖ¤¼Ù˵£¬Äâ½ÓÄɶàÖÖÄâÈË“¹ýʳ·Ê¸Êºñζ”Χ¾ø¾ÆÚÖ¬´úлÔÓÂÒ¶¯ÎïÄ£×Ó£¬´ÓÕûÌå¡¢Æ÷¹Ù¡¢·Ö×ӵȶà²ãÑо¿¹ú²ÝÒû¸ÄÉÆΧ¾ø¾ÆÚÉñ¾-ÄÚÉø͸-ÃâÒß-´úлÔÓÂҵĹ¦Ð§£»²¢Öصã»ùÓÚ“Âѳ²-¸Î/³¦Öá”FSH/E2ÐźÅͨ·£¬Õ¹ÏÖÆä·Ö×ÓÉúÎïѧ»úÖÆ¡£
ÌúƤʯõú£¬Ó°ÏìÌìϵÄÖйúÖ²Îï
ºã·åg22×÷ΪÖйúÌúƤʯõúÁúÍ·ÆóÒµ£¬½¨Éè25ÄêÀ´Ê¼ÖÕÖÂÁ¦ÓÚÌúƤʯõúµÄÈ«¹¤ÒµÁ´´òÔ죬²¢Í¨¹ý¿Æ¼¼Á¢ÒìÈùŰåÖÐÒ½Ò©¹¤Òµ»À·¢³öÁËлú¡£¹«Ë¾×¤×ã¿ÆÑУ¬ÒÀÍÐÉɽ¿µ½¡Ð¡ÕòÕã½ÔºÊ¿Ö®¼Ò£¬¼á³ÖÓë¿ÆÑÐԺУ¿ªÕ¹²úѧÑÐÏàÖú£¬ÉîÈ뿪չҩÀíҩЧ»úÀíÑо¿£¬ÌØÊâÊÇÔÚÌúƤʯõú´ó¿µ½¡²úÆ·µÄ¿ª·¢·½Ãæ¾ùÈ¡µÃÁËÓÅÒìµÄЧ¹û¡£
2017Ä꣬ÓɳÂËغìÑо¿Ô±ÎªÏîÄ¿×ÜÈÏÕæÈË¡¢ºã·åg22ǣͷ¼ç¸º,Õã½¹¤Òµ´óѧ¡¢Õã½ÖÐÒ½Ò©´óѧµÈ5Ëù¸ßУ¡¢7¼ÒÆóÒµÅäºÏÉ걨µÄ“ÌúƤʯõú´ó¿µ½¡²úÆ·Ñз¢”ÏîÄ¿ÀÖ³ÉÈëÑ¡¹ú¼Ò“Ê®ÈýÎå”ÖصãÑз¢ÍýÏë“ÖÐÒ½Ò©ÏÖ´ú»¯Ñо¿”רÏî¡£Ñо¿Ð§¹ûÏȺó»ñ¹ú¼ÒÖصãÑз¢ÍýÏëÏîÄ¿¡¢¹ú¼Ò×ÔÈ»¿Æѧ»ù½ð10ÓàÏÔÚFoodFunction¡¢FrontPharmacol¡¢IntJ BiolMacromolµÈº£ÄÚÍâÆÚ¿¯½ÒÏþÌúƤʯõúÏà¹ØÂÛÎÄ31ƪ£¬Óùú¼ÊͨÓõē¿ÆѧÓïÑÔ”ÈÃÌúƤʯõúÕâ¸öÓ°ÏìÌìϵÄÖйúÖ²Îï»ñµÃÈ«ÌìϵÄÆÕ±éÈÏ¿É£¡
½üÊ®Ä꣬¹ú¼Ò¸ß¶ÈÖØÊÓÖÐÒ½Ò©´«³ÐÁ¢ÒìÊÂÇ飬¹ú¼Ò×ÔÈ»¿Æѧ»ù½ð¶ÔÖÐÒ½Ò©ÁìÓò¾ÙÐÐÁËÖØ´óÏîÄ¿µÄ½á¹¹¡£´Ë´Î£¬¹ú²ÝÌúƤʯõúÒûÆ·»ñµÃÁ¢ÏîÅú×¼£¬ÊÚÓèÕþ²ßºÍ¾·ÑÖ§³Ö£¬¹ú²ÝÑз¢ÍŶӵÄÆð¾¢ÐÔ»ñµÃ¼«´óµÄÒý·¢£¬Ò²±ê¼Ç׏ú²Ý¿ÆÑн¹µã¾ºÕùÁ¦½øÒ»²½ÔöÇ¿¡£
δÀ´£¬¹ú²Ý½«ÒÀÍÐ×ÔÉí¿ÆÑÐʵÁ¦£¬³ä·Öµ÷¶¯¿ÆÑÐÆð¾¢ÐÔ£¬Ò»Ö±Ìá¸ß¿ÆÑÐÄÜÁ¦£¬´´Á¢¸ßÖÊÁ¿Ð§¹û£¬Íƶ¯ÖÐÒ½Ò©¹¤ÒµÉú³¤£¬ÕùÈ¡ÔÚÖÐÒ½Ò©´«³Ð¿ÆÑÐÊÂÇéÉÏÈ¡µÃ¸ü¶à¼Ñ¼¨£¡